KMID : 0988920160140030258
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Intestinal Research 2016 Volume.14 No. 3 p.258 ~ p.263
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Change in the diagnosis of inflammatory bowel disease: a hospital-based cohort study from Korea
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Lee Ho-Su
Choe Jae-Won Lee Hyo-Jeong Hwang Sung-Wook Park Sang-Hyoung Yang Dong-Hoon Kim Kyung-Jo Ye Byong-Duk Byeon Jeong-Sik Myung Seung-Jae Yoon Yong-Sik Yu Chang-Sik Kim Jin-Ho Yang Suk-Kyun
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Abstract
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Background/Aims: Accurately diagnosing inflammatory bowel disease (IBD) remains a challenge, but is crucial for providing proper management for affected patients. The aim of the present study was to evaluate the frequency of change in diagnosis in Korean patients who were referred to our institution with a diagnosis of IBD.
Methods: We enrolled 1,444 patients diagnosed with ulcerative colitis (UC) and 1,452 diagnosed with Crohn's disease (CD), who had been referred to the Asan Medical Center between January 2010 and December 2014. These patients were assessed and subsequently classified as having UC, CD, indeterminate colitis, possible IBD, or non-IBD.
Results; During a median follow-up of 15.9 months, 400 of the 2,896 patients (13.8%) analyzed in this study experienced a change in diagnosis. A change in diagnosis from UC to CD, or vice-versa, was made in 24 of 1,444 patients (1.7%) and 23 of 1,452 patients (1.6%), respectively. A change to a non-IBD diagnosis was the most common modification; 7.5% (108 of 1444) and 12.7% (184 of 1452) of the patients with a referral diagnosis of UC and CD, respectively, were reclassified as having non-IBD. Among the 292 patients who were ultimately determined not to have IBD, 135 (55 UC and 80 CD cases) had received IBD-related medication.
Conclusions: There are diagnostic uncertainties and difficulties in relation to IBD. Therefore, precise assessment and systematic follow-up are essential in the management of this condition.
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KEYWORD
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Crohn disease, Ulcerative colitis, Diagnosis, Inflammatory bowel diseases
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